Common antibiotic tested to halt lung decline in HIV patients

NCT ID NCT05382208

Summary

This study is testing whether a common antibiotic, doxycycline, can slow down the worsening of emphysema in people living with HIV. About 133 participants with both HIV and emphysema will take either doxycycline or a placebo pill twice daily for 72 weeks. Researchers will measure changes in lung function, walking ability, and quality of life to see if the treatment helps control the lung disease.

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Contacts and locations

Locations

  • Case Western University

    Cleveland, Ohio, 44106, United States

  • Duke University School of Medicine

    Durham, North Carolina, 27704, United States

  • Emory University

    Atlanta, Georgia, 30329, United States

  • Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Miami University

    Miami, Florida, 33136, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • SUNY Downstate Medical School

    Brooklyn, New York, 11203, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • Tulane University

    New Orleans, Louisiana, 70112, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of California Los Angeles

    Los Angeles, California, 90095, United States

  • University of California San Diego

    San Diego, California, 92103, United States

  • University of Cincinnati College of Medicine

    Cincinnati, Ohio, 45267, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15261, United States

  • University of Texas, McGovern Medical School

    Houston, Texas, 77030, United States

  • University of Washington

    Seattle, Washington, 98104, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.