Old antibiotic, new hope: doxycycline tested for HIV-Related emphysema
NCT ID NCT05382208
First seen Feb 01, 2026 · Last updated May 16, 2026 · Updated 15 times
Summary
This study tests whether the common antibiotic doxycycline can slow the worsening of emphysema in people living with HIV. About 133 current or former smokers with HIV will take doxycycline for 72 weeks. Researchers will measure lung function, walking ability, and check for antibiotic resistance. The goal is to see if doxycycline can help control this lung disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western University
Cleveland, Ohio, 44106, United States
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Duke University School of Medicine
Durham, North Carolina, 27704, United States
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Emory University
Atlanta, Georgia, 30329, United States
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Miami University
Miami, Florida, 33136, United States
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Ohio State University
Columbus, Ohio, 43210, United States
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SUNY Downstate Medical School
Brooklyn, New York, 11203, United States
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Temple University
Philadelphia, Pennsylvania, 19140, United States
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Tulane University
New Orleans, Louisiana, 70112, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of California Los Angeles
Los Angeles, California, 90095, United States
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University of California San Diego
San Diego, California, 92103, United States
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University of Cincinnati College of Medicine
Cincinnati, Ohio, 45267, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15261, United States
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University of Texas, McGovern Medical School
Houston, Texas, 77030, United States
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University of Washington
Seattle, Washington, 98104, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Weill Cornell Medicine
New York, New York, 10065, United States
Conditions
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