Double shock may save more cardiac arrest victims
NCT ID NCT07174986
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether using two defibrillators in sequence, instead of the standard single defibrillator, can improve survival in people whose hearts are in a shockable rhythm but don't respond to the first shock. About 916 adults with out-of-hospital cardiac arrest will be randomly assigned to either the double-shock approach or standard care. The main goal is to see if more patients are alive at 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Double sequential defibrillation (using two defibrillators)
What this could lead to
If it works, this could become a new standard emergency procedure to save more lives in cardiac arrest.
What could go wrong
This is an early combined Phase 2/3 trial, so results are uncertain. The benefit seen in a prior study may not hold in this broader group.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ARREST (AmsteRdam REsuscitation STudies)
NOT_YET_RECRUITINGAmsterdam, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Ambulanshelikoptern (HEMS) Västra Götalandsregionen
RECRUITINGKungälv, Västra Götaland County, 442 83, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Ambulanssjukvården Region Värmland
RECRUITINGKarlstad, Värmland County, 65230, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Ambulanssjukvården Skaraborgs Sjukhus, Västra Götalandsregionen (SKAS)
RECRUITINGSkövde, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Ambulanssjukvården, Region Halland
RECRUITINGHalmstad, Halland County, Sweden
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centro de Emergencias 061 Andalucía
NOT_YET_RECRUITINGMálaga, Andalusia, 29560, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emergency medical services NU-Sjukvården, Region Västra Götaland
RECRUITINGTrollhättan, 461 85, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Emergency medical services, Södra Älvsborgs Sjukhus, Region Västra Götaland
RECRUITINGBorås, 501 82, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Médico Emergencias Osakidetza EMERGENTZIAK
NOT_YET_RECRUITINGBilbao, Baque Country, 48004, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Prehospital Intensive Care Unit (PIV) AnOPIVA Östra Sjukhuset/SU
RECRUITINGGothenburg, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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SUMMA 112 Emergency medical services
NOT_YET_RECRUITINGMadrid, Madrid, 28045, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Shalgrenska University Hospital
RECRUITINGGothenburg, Sweden
Contact Email: •••••@•••••
Contact
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Sistema de Emergencias Medicas de Catalunya
NOT_YET_RECRUITINGBarcelona, Catalonia, 08908, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Sjukvården i väster
RECRUITINGAlingsås, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact