New gout drug aims to beat allopurinol in major trial

NCT ID NCT07089875

Recruiting now Disease control Sponsor: Crystalys Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This study tests a new medicine called dotinurad against the standard drug allopurinol for lowering uric acid in adults with gout. About 500 people who have had at least two gout flares in the past year will take either dotinurad or allopurinol for 24 weeks. The main goal is to see if dotinurad can lower uric acid levels below 6.0 mg/dL more effectively than allopurinol.

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Conditions

The condition(s) this trial relates to.

gout Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GOUT

Contacts and locations

Locations

Accellacare - Alcobendas
RECRUITING

Alcobendas, Madrid, 28100, Spain
Acclaim Clinical Research, Inc.
RECRUITING

San Diego, California, 92120, United States
Alabama Clinical Therapeutics
WITHDRAWN

Birmingham, Alabama, 35235, United States
Alliance Clinical Lewisville (Epic Clinical Research)
RECRUITING

Lewisville, Texas, 75057, United States
Altoona Center for Clinical Research
RECRUITING

Duncansville, Pennsylvania, 16635, United States
Amicis Research Center - Balboa
RECRUITING

Northridge, California, 91324, United States
Anchor Medical Research, LLC
RECRUITING

Miami, Florida, 33176, United States
Arizona Arthritis & Rheumatology Associates (AARA) - Gilbert
RECRUITING

Gilbert, Arizona, 85297, United States
Arizona Arthritis & Rheumatology Associates (AARA) - Glendale
RECRUITING

Glendale, Arizona, 85306, United States
Arizona Arthritis & Rheumatology Associates (AARA) - Mesa
RECRUITING

Mesa, Arizona, 85110, United States
BTC Network - Encompass Clinical Research
RECRUITING

Spring Valley, California, 91978, United States
Best Quality Research
RECRUITING

Hialeah, Florida, 33016, United States
Bradenton Research Center
RECRUITING

Bradenton, Florida, 34205, United States
Carteret Medical Group LLC
RECRUITING

Morehead City, North Carolina, 28557, United States
Centrum Medyczne Solumed
RECRUITING

Poznan, Greater Poland Voivodeship, 60-529, Poland
Charlottesville Medical Research
RECRUITING

Charlottesville, Virginia, 22911, United States
Chicago Clinical Research Institute, Inc. (CCRII)
RECRUITING

Chicago, Illinois, 60607, United States
ClinicMed Daniluk, Nowak Spółka Komandytowa
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-879, Poland
Clinical Research Institute of Michigan - St. Clair Shores
RECRUITING

Saint Clair Shores, Michigan, 48081, United States
Clinical Research Trials of Florida
RECRUITING

Tampa, Florida, 33607, United States
Clinical Research of Center Florida
RECRUITING

Lakeland, Florida, 33805, United States
Clínica Gaias Santiago
RECRUITING

Santiago de Compostela, La Coruña, 15706, Spain
Clínica NTDE - Nuevas Tecnologías en Diabetes y Endocrinología
RECRUITING

Seville, Sevilla, 46010, Spain
Coastal Carolina Research Center - Main
RECRUITING

North Charleston, South Carolina, 29405, United States
Cohen Medical Centers
RECRUITING

Thousand Oaks, California, 91360-3967, United States
Complejo Hospitalario Universitario A Coruña
RECRUITING

A Coruña, La Coruña, 15006, Spain
Conquest Research - Winter Park
RECRUITING

Winter Park, Florida, 32789, United States
D&H Pompano Research Center
RECRUITING

Pompano Beach, Florida, 33064, United States
DM Clinical Research - Detroit
WITHDRAWN

Southfield, Michigan, 48076, United States
DM Clinical Research - Tomball - Multiple Specialties
RECRUITING

Tomball, Texas, 77375, United States
Del Sol Research Management - Tucson
RECRUITING

Tucson, Arizona, 85715, United States
Del Sol Research Management - Tucson East
RECRUITING

Tucson, Arizona, 85715, United States
DelRicht Research
RECRUITING

Charlotte, North Carolina, 28210, United States
DelRicht Research - Atlanta
WITHDRAWN

Atlanta, Georgia, 30329, United States
DelRicht Research - Hendersonville
WITHDRAWN

Hendersonville, Tennessee, 37075, United States
DelRicht Research - LCMC Health Urgent Care - Lakeview
RECRUITING

New Orleans, Louisiana, 70124, United States
DelRicht Research - Louisville (Derby City DPC)
RECRUITING

Louisville, Kentucky, 40205, United States
DelRicht Research - Maryland (Matthew L. Mintz, MD, FACP)
WITHDRAWN

Rockville, Maryland, 20852, United States
DelRicht Research - Prairieville
RECRUITING

Prairieville, Louisiana, 70769, United States
DelRicht Research - Town and Country
RECRUITING

Town and Country, Missouri, 63017, United States
DelRicht Research - Tulsa
WITHDRAWN

Tulsa, Oklahoma, 74133, United States
Delricht Research - Better Life Direct Primary Care
WITHDRAWN

Indianapolis, Indiana, 46202, United States
Delricht Research - Command Family Medicine
WITHDRAWN

Springfield, Missouri, 65807, United States
Delricht Research - Concierge And Direct Primary Care
RECRUITING

Overland Park, Kansas, 66223, United States
Delricht Research - Concierge Medicine Of Cincinnati
WITHDRAWN

Mason, Ohio, 45040, United States
Denver Arthritis Clinic - Lowry
RECRUITING

Denver, Colorado, 80230, United States
Digestive Health Research of North Texas
RECRUITING

Wichita Falls, Texas, 76301, United States
Discovery Clinical Trials
RECRUITING

San Antonio, Texas, 78229, United States
Dream Team Clinical Research
WITHDRAWN

Pomona, California, 91767, United States
ERG - Endeavor Clinical Trials
RECRUITING

San Antonio, Texas, 78240, United States
East Bay Rheumatology Medical Group
RECRUITING

San Leandro, California, 94578, United States
Ellipsis Research Group
RECRUITING

Brooklyn, New York, 11215, United States
Epic Medical Research - DeSoto
RECRUITING

DeSoto, Texas, 75115, United States
Flourish Chicago - Ravenswood (Great Lakes Clinical Trials)
RECRUITING

Chicago, Illinois, 60640, United States
FutureMeds - Krakow
RECRUITING

Krakow, Lesser Poland Voivodeship, 31-501, Poland
FutureMeds - Targówek
RECRUITING

Warsaw, Masovian Voivodeship, 03-291, Poland
FutureMeds - Wroclaw
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 53-673, Poland
FutureMeds Gdynia
RECRUITING

Gdynia, Pomeranian Voivodeship, 81-537, Poland
Health Awareness Inc
RECRUITING

Jupiter, Florida, 33458, United States
Health Concepts
RECRUITING

Rapid City, South Dakota, 57702, United States
Healthcare Research Network
WITHDRAWN

Hazelwood, Missouri, 63042, United States
Healthcare Research Network - Tinley Park
RECRUITING

Flossmoor, Illinois, 60402, United States
Herco Medical and Research Center, Inc
RECRUITING

Coral Gables, Florida, 33134, United States
Hometown Urgent Care and Research - Dayton
RECRUITING

Dayton, Ohio, 45424, United States
Hospital Quirónsalud Infanta Luisa
RECRUITING

Seville, Sevilla, 41010, Spain
Hospital Universitario Infanta Leonor
RECRUITING

Madrid, Madrid, 28032, Spain
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08041, Spain
Infinity Clinical Research
RECRUITING

Norco, California, 92860, United States
Innova Clinic
RECRUITING

Plońsk, Masovian Voivodeship, 09-100, Poland
Inter Clinic
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-077, Poland
Investigators Research Group
RECRUITING

Brownsburg, Indiana, 46112, United States
Las Vegas Clinical Trials
RECRUITING

North Las Vegas, Nevada, 89030, United States
Lone Star Arthritis & Rheumatology Associates - Denton
RECRUITING

Denton, Texas, 76205, United States
MD Medical Research - Oxon Hill
RECRUITING

Oxon Hill, Maryland, 20745, United States
Med-Progress Ośrodek Nowoczesnego Leczenia
RECRUITING

Wejherowo, Pomeranian Voivodeship, 84-200, Poland
MedVadis Research
RECRUITING

Waltham, Massachusetts, 02451, United States
MediSphere Medical Research Center, LLC
RECRUITING

Evansville, Indiana, 47714, United States
Medicover Integrated Clinical Services- MICS Centrum Medyczne Warszawa Chlodna
RECRUITING

Warsaw, Masovian Voivodeship, 00-872, Poland
Medvin Clinical Research - Covina
RECRUITING

Covina, California, 91722, United States
Medvin Clinical Research - Tujunga
RECRUITING

Tujunga, California, 91042, United States
Michigan Medicine - University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109-5000, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
New Generation of Medical Research
RECRUITING

Hialeah, Florida, 32016, United States
Oakland Medical Center
RECRUITING

Troy, Michigan, 48085, United States
Omega Research DeBary
RECRUITING

Orlando, Florida, 32808, United States
Panax Clinical Research
RECRUITING

Miami Lakes, Florida, 33014, United States
Pioneer Research Solutions
RECRUITING

Houston, Texas, 77099, United States
Premier Health Research
RECRUITING

Sparta, New Jersey, 07871, United States
Pro Familia - Katowice
RECRUITING

Katowice, Silesian Voivodeship, 40-122, Poland
Prolato Clinical Research Center
RECRUITING

Houston, Texas, 77027, United States
Prolato Clinical Research Center
RECRUITING

Sochaczew, Masovian Voivodeship, 96-500, Poland
R & H Clinical Research - Westborough Drive
RECRUITING

Katy, Texas, 77449, United States
Revive Research Institute - Sterling Heights
RECRUITING

Sterling Heights, Michigan, 48313, United States
Shelby Clinical Research, LLC - North Carolina
RECRUITING

Shelby, North Carolina, 28150, United States
Siena Research Network
RECRUITING

Sugar Land, Texas, 77479, United States
Silmedic sp. z o.o.
RECRUITING

Katowice, Silesian Voivodeship, 40-282, Poland
Southwest Rheumatology Research
RECRUITING

Mesquite, Texas, 75150, United States
Suburban Research Associates - West Chester Office
WITHDRAWN

West Chester, Pennsylvania, 19380, United States
Tandem Clinical Research - Metairie Clinic
ACTIVE_NOT_RECRUITING

Metairie, Louisiana, 70006, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States
Velocity Clinical Research - San Bernardino
RECRUITING

San Bernardino, California, 92408, United States
West Coast Research
RECRUITING

Dublin, California, 94568, United States
Zenos Clinical Research
RECRUITING

Dallas, Texas, 75230, United States

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