Dopamine drug may lift brain fog and slow steps in elderly depression
NCT ID NCT04469959
First seen Feb 06, 2026 · Last updated May 12, 2026 · Updated 15 times
Summary
This study looks at whether a drug that increases dopamine (carbidopa/levodopa) can improve thinking speed, walking, and mood in older adults with depression. About 100 people aged 60 and older with depression and slow thinking or walking will take the drug or a placebo. The goal is to see if boosting dopamine helps with symptoms that don't always get better with standard antidepressants.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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Vanderbilt Psychiatric Hospital
Nashville, Tennessee, 37212, United States
Conditions
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