Can a dementia drug silence ringing ears?
NCT ID NCT07153991
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether donepezil, a drug used for dementia, can help people with chronic tinnitus (ringing in the ears). 70 adults with long-term tinnitus received either donepezil or a placebo for 3 months. Researchers measured changes in tinnitus severity using standard questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- donepezil
- What this could lead to
- If it works, this could point toward a medication to reduce the severity of chronic tinnitus symptoms.
- What could go wrong
- This is a small, early-phase trial with only 70 participants. The drug may not improve tinnitus more than a placebo, and side effects like nausea or dizziness are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universidade De São Paulo
São Paulo, São Paulo, 04356080, Brazil
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