Can a dementia drug silence ringing ears?
NCT ID NCT07153991
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether donepezil, a drug used for dementia, can help people with chronic tinnitus (ringing in the ears). 70 adults with long-term tinnitus received either donepezil or a placebo for 3 months. Researchers measured changes in tinnitus severity using standard questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
donepezil
What this could lead to
If it works, this could point toward a medication to reduce the severity of chronic tinnitus symptoms.
What could go wrong
This is a small, early-phase trial with only 70 participants. The drug may not improve tinnitus more than a placebo, and side effects like nausea or dizziness are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Universidade De São Paulo
São Paulo, São Paulo, 04356080, Brazil