New drug trial targets Alzheimer's risk in down syndrome

NCT ID NCT06911944

Summary

This study is testing whether the drug donanemab can reduce the buildup of a harmful protein called amyloid in the brains of adults with Down syndrome. About 60 participants, aged 35-50, will receive monthly infusions of either donanemab or a placebo for one year, followed by an optional second year. The main goals are to see if the drug lowers brain amyloid levels and is safe and well-tolerated in this population.

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