Sound waves may help chemo reach deadly childhood brain tumors

NCT ID NCT05630209

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special ultrasound device can safely open the blood-brain barrier in children with a rare, aggressive brain tumor called DIPG. By temporarily allowing the chemotherapy drug doxorubicin to reach the tumor, researchers hope to improve treatment. The study involves 10 children aged 5 to 21 and focuses on safety and how well the barrier opens.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cook Children's Health Care System

    Fort Worth, Texas, 76104, United States

  • Nicklaus Children's Hospital

    Miami, Florida, 33155, United States

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