Heart drug repurposed to fight deadly brain tumor in kids

NCT ID NCT06701812

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests whether digoxin, a common heart medication, can help children and young adults (ages 1 to 29) with a specific type of relapsed brain cancer called non-WNT/non-SHH medulloblastoma. Participants must have already had chemotherapy and radiation. The main goal is to see how many patients are alive without their cancer growing 4 months after starting treatment. About 23 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arkansas Childrens Hospital

    RECRUITING

    Little Rock, Arkansas, 72202, United States

    Contact

  • Children's National Medical Center

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact

  • Connecticut Children's Medical Center

    NOT_YET_RECRUITING

    Hartford, Connecticut, 06106, United States

    Contact

  • Johns Hopkins All Children's

    NOT_YET_RECRUITING

    St. Petersburg, Florida, 33701, United States

    Contact

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21218, United States

    Contact

  • Levine Cancer Institute

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact

  • Nemours Jacksonville

    NOT_YET_RECRUITING

    Jacksonville, Florida, 32207, United States

    Contact

  • St. Joseph's Children's Hospital

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact

  • UNC Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact

  • UT Southwestern

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

    Contact

  • University of Alabama at Birmingham Children's of Alabama

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact

  • University of Miami

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

  • Washington University St. Louis

    RECRUITING

    St Louis, Missouri, 63130, United States

    Contact

Conditions

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