Can a phone app ease Schizophrenia's 'Negative' symptoms?
NCT ID NCT06791122
First seen Nov 01, 2025
Summary
This study tests a smartphone app called CT-155 designed to help people with schizophrenia manage negative symptoms like low motivation and reduced pleasure. About 262 adults with schizophrenia will use the app for 16 weeks, with an optional extension. Researchers will track symptom changes, app usage, and healthcare visits over about a year.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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ATP Clinical Research, Inc.
Orange, California, 92866, United States
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Atrium Health
Charlotte, North Carolina, 28211, United States
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Beaumont Psychiatry Clinic
Beaumont, Texas, 77706, United States
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Boston Neurobehavioral Associates
Brookline, Massachusetts, 02446, United States
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CT Clinical Research
Cromwell, Connecticut, 06416, United States
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Center for Behavioral Health, LLC
Gaithersburg, Maryland, 20877, United States
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Collaborative Neuroscience Research
Torrance, California, 90504, United States
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Emory University
Atlanta, Georgia, 30303, United States
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Galiz Research
Hialeah, Florida, 33106, United States
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Global Life Research Network
Miami, Florida, 33155, United States
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Health Synergy Clinical Research, LLC
West Palm Beach, Florida, 33407, United States
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IMA Clinical Research Las Vegas
Las Vegas, Nevada, 89102, United States
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Interventional Psychiatry of Tampa Bay
Tampa, Florida, 33629, United States
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NRC Research Institute
Orange, California, 92868, United States
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Neurobehavioral Research, Inc.
Cedarhurst, New York, 11516, United States
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New Life Medical Research Center, Inc.
Hialeah, Florida, 88012, United States
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North Country Clinical Research Inc
Oceanside, California, 92054, United States
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Psychiatric Consultants,PC
Franklin, Tennessee, 37067, United States
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Red Oak Psychiatry Associates, PA
Houston, Texas, 77090, United States
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Richmond Behavioral Associates
Staten Island, New York, 10314, United States
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Rivus Wellness and Research Institute
Oklahoma City, Oklahoma, 73112, United States
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SMS Clinical Research
Mesquite, Texas, 75149, United States
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Salem VA Medical Center
Salem, Virginia, 24153, United States
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Sheppard Pratt Physicians's Practice Association, Inc.
Baltimore, Maryland, 21204, United States
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St. Charles Psychiatric Associates & Midwest Research Group
Saint Charles, Missouri, 63304, United States
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Stanford University Medical Center
Stanford, California, 94304, United States
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Sun Valley Behavioral Med Center
Imperial, California, 92251, United States
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University of California San Diego
La Jolla, California, 92093, United States
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University of Massachusetts - Worcester
Worcester, Massachusetts, 01655, United States
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University of Miami
Miami, Florida, 33136, United States
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Western Michigan University
Kalamazoo, Michigan, 49048, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
smartphone app (CT-155)
What this could lead to
If it works, this app could offer a new way to help people with schizophrenia manage difficult symptoms like lack of motivation and enjoyment.
What could go wrong
This is an early-stage study with no placebo comparison, so results may not be conclusive. The app may not work for everyone, and participants must be willing to use a smartphone regularly.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.