Dietary oxysterols linked to diabetes risk in african americans

NCT ID NCT05072587

Completed Knowledge-focused Sponsor: Morehouse School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study looked at whether removing oxysterols (harmful compounds in cooked animal foods) from the diet could improve insulin production in African Americans with prediabetes or early type 2 diabetes. Twelve participants ate a plant-based diet free of oxysterols for a period. Researchers measured changes in insulin function and blood sugar control. The goal was to see if this diet could lower diabetes risk in a high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Plant-based diet without oxysterols
What this could lead to: If this diet improves insulin production, it could point toward a dietary approach to lower type 2 diabetes risk in African Americans.
What could go wrong: This was a very small pilot study (12 people) with no control group, so results may not apply broadly. Dietary changes can be hard to maintain long-term.

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Conditions

The condition(s) this trial relates to.

prediabetes syndrome type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES

Contacts and locations

Locations

Morehouse School of Medicine

Atlanta, Georgia, 30310, United States

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