Psoriasis relief on a plate? diet trial tests wheat and dairy elimination

NCT ID NCT05644782

Recruiting now Symptom relief Sponsor: University of Palermo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether removing wheat and cow's milk from the diet can reduce inflammation and improve skin symptoms in people with mild-to-moderate psoriasis. 82 participants will follow either a wheat- and dairy-free diet or a control diet for 2 months, then some will be re-exposed to wheat to see if symptoms return. The goal is to understand the link between diet, gut health, and psoriasis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: wheat- and dairy-free diet
What this could lead to: If it works, this could point toward a simple dietary change to help manage psoriasis symptoms.
What could go wrong: This is a small, early-stage trial with no blinding, so results may be influenced by placebo effects. The diet is restrictive and may be hard to follow long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

celiac disease psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLUTEN SENSITIVITY PSORIASIS

Contacts and locations

Locations

Dermatology Department of the University Hospital 'P. Giaccone' of Palermo, Italy,
RECRUITING

Palermo, Palermo, 90127, Italy
Internal Medicine Department of the University Hospital of Palermo
RECRUITING

Palermo, Palermo, 90127, Italy
Internal Medicine Division of the "Cervello-Villa Sofia" Hospital
RECRUITING

Palermo, PA, 90146, Italy

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