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Can a brazilian diet plus supplements tame inherited high cholesterol?

NCT ID NCT06331195

Ongoing Disease control Sponsor: Hospital do Coracao Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a special heart-friendly diet, with or without added plant sterols and krill oil, can improve cholesterol levels in people with familial hypercholesterolemia (a genetic condition causing very high cholesterol). About 300 participants will follow the diet and take either placebo or the supplements for 120 days. The goal is to see if these additions help lower LDL cholesterol and lipoprotein(a) better than diet alone.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FAMILIAL HYPERCHOLESTEROLEMIA

Contacts and locations

Locations

  • Centro Oncológico de Roraima

    Boa Vista, Brazil

  • Centro de Estudos e Pesquisas em Moléstias Infecciosas

    Natal, Brazil

  • Centro de Pesquisa Cardiolima

    Teresina, Brazil

  • Centro de Pesquisa Silvestre Santé

    Rio Branco, Brazil

  • Centro de Pesquisas Clínicas Dr. Marco Mota

    Maceió, Brazil

  • Hcor

    São Paulo, São Paulo, Brazil

  • Hospital Ana Nery

    Salvador, Brazil

  • Hospital Oto Aldeota

    Fortaleza, Brazil

  • InCor

    São Paulo, Brazil

  • Instituto Dante Pazzanese de Cardiologia

    São Paulo, Brazil

  • Instituto Nacional de Cardiologia

    Rio de Janeiro, Brazil

  • Instituto de Cardiologia e Transplantes do DF

    Brasília, Brazil

  • Instituto de Pesquisa e Ensino em Saúde

    Porto Velho, Brazil

  • OCARA

    Belém, Brazil

  • Santa Casa de Montes Claros

    Montes Claros, Brazil

  • Universidade Estadual de Maringá

    Maringá, Brazil

  • Universidade Federal de Goiás

    Goiânia, Brazil

  • Universidade Federal de São Paulo

    São Paulo, Brazil

  • Universidade Federal do Amapá

    Macapá, Brazil

  • Universidade Federal do Amazonas

    Manaus, Brazil

  • Universidade Federal do Mato Grosso

    Cuiabá, Brazil

  • Universidade Federal do Tocantins

    Palmas, Brazil

  • Universidade Federal do Vale do São Francisco

    Petrolina, Brazil

  • Universidade do Mato Grosso do Sul

    Campo Grande, Brazil

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