Can a new Omega-3 molecule bypass fat digestion?
NCT ID NCT07771309
First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time
Summary
This trial tests whether a new form of omega-3, called DHA-taurine, is absorbed better than a standard omega-3 supplement when taken without food. Healthy men aged 18 to 30 receive both supplements on separate days, and researchers measure DHA levels in the blood over 8 hours. The goal is to see if DHA-taurine can deliver omega-3s even when normal fat digestion is limited, which could help people with fat absorption issues.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- DHA-taurine (a novel omega-3 supplement) compared with DHA ethyl ester (a conventional omega-3 supplement)
- What this could lead to
- If DHA-taurine is absorbed well without food, it could lead to omega-3 supplements that work for people with fat absorption problems or low-fat diets.
- What could go wrong
- This is a very small early study in healthy young men, so results may not apply to broader populations. The new molecule may not absorb better than the standard form.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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6 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male * Healthy * Age between 18 and 30 years * Body mass index between 18.5-25 kg/m2 * Informed consent * Moderate level of physical activity Exclusion Criteria: * Use of fish-oil/omega-3 FA supplements within the last 3 months * Regular tobacco smoking or use of other nicotine-containing products * Allergy or intolerance to ingredients included in the standardised meals * Weekly intake of fish \>350 g (23) * First-degree relatives with diabetes and/or glycated haemoglobin (HbA1c) \>48 mmol/mol, familial hypercholesterolemia/hyperlipidaemia * Anaemia (haemoglobin below 8.3 mmol/L) * Alanine aminotransferase (ALAT) and/or aspartate aminotransferase (ASAT) \>2 times upper normal values (Normal values: ALAT \< 70 U/L, ASAT \<45 U/L) * Nephropathy (serum creatinine \>105 μmol/L) and/or albuminuria (\>30 mg/g albumin in urine)) * History of hepatobiliary or gastrointestinal disorder(s) * Any physical or psychological condition, or ongoing medication, that the investigator evaluates would interfere with trial participation, including any acute or chronic illnesses
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Biomedical Sciences, University of Copenhagen
Copenhagen, 2200, Denmark
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