New hope for kids with aggressive brain cancer: DFMO trial targets relapse
NCT ID NCT04696029
First seen Feb 03, 2026 · Last updated May 10, 2026 · Updated 15 times
Summary
This study tests a drug called DFMO as a maintenance therapy to prevent cancer from coming back in children with high-risk medulloblastoma. The trial enrolls 118 participants aged 0-21 who have molecular high-risk, very high-risk, or relapsed/refractory disease. Researchers will measure how long children remain cancer-free and overall survival compared to historical data.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MEDULLOBLASTOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Advocate Aurora Research Institute
RECRUITINGChicago, Illinois, 60453, United States
Contact Email: •••••@•••••
Contact
-
All Children's Hospital Johns Hopkins Medicine
RECRUITINGSt. Petersburg, Florida, 33701, United States
Contact
Contact Email: •••••@•••••
-
Arkansas Children's Hospital
RECRUITINGLittle Rock, Arkansas, 72202, United States
Contact
Contact Email: •••••@•••••
-
Arnold Palmer Hospital for Children
RECRUITINGOrlando, Florida, 32806, United States
Contact
Contact Email: •••••@•••••
-
CHUQ
RECRUITINGQuébec, Quebec, QC G1V 4W6, Canada
Contact
Contact Email: •••••@•••••
-
Cardinal Glennon Children's Medical Center
RECRUITINGSt Louis, Missouri, 63104, United States
Contact Email: •••••@•••••
Contact
-
Children's Mercy Hospitals and Clinics
RECRUITINGKansas City, Missouri, 64108, United States
Contact
Contact Email: •••••@•••••
-
Connecticut Children's Hospital
RECRUITINGHartford, Connecticut, 06106, United States
Contact Email: •••••@•••••
Contact
-
Dell Children's Blood and Cancer Center
RECRUITINGAustin, Texas, 78723, United States
Contact Email: •••••@•••••
Contact
-
Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact
Contact Email: •••••@•••••
-
Hasbro Children's Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact
Contact Email: •••••@•••••
-
Kapiolani Medical Center for Women and Children
RECRUITINGHonolulu, Hawaii, 96813, United States
Contact Email: •••••@•••••
Contact
-
Kentucky Children's Hospital
RECRUITINGLexington, Kentucky, 40502, United States
Contact Email: •••••@•••••
Contact
-
Levine Children's Hospital
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Email: •••••@•••••
Contact
-
Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
Contact
Contact Email: •••••@•••••
-
Nicklaus Children's Hospital
RECRUITINGMiami, Florida, 33155, United States
Contact Email: •••••@•••••
Contact
-
Norton Children's Research Institute/Affiliated with University of Louisville School of Medicine
RECRUITINGLouisville, Kentucky, 40202, United States
Contact
Contact
-
Penn State Milton S. Hershey Medical Center and Children's Hospital
RECRUITINGHershey, Pennsylvania, 17033, United States
Contact Email: •••••@•••••
Contact
-
Rady Children's Hospital
RECRUITINGSan Diego, California, 92123, United States
Contact Email: •••••@•••••
Contact
-
Randall Children's Hospital
RECRUITINGPortland, Oregon, 97227, United States
Contact Email: •••••@•••••
Contact
-
St. Joseph's Children's Hospital
RECRUITINGTampa, Florida, 33607, United States
Contact
Contact Email: •••••@•••••
-
Stanford University
RECRUITINGStanford, California, 94305, United States
Contact
Contact Email: •••••@•••••
-
UCSF Benioff Children's Hospital Oakland
RECRUITINGOakland, California, 94609, United States
Contact
Contact Email: •••••@•••••
-
University of Oklahoma
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Email: •••••@•••••
Contact
Conditions
Explore the condition pages connected to this study.