Can a common sedative keep agitated lung patients off ventilators?

NCT ID NCT06567587

Completed Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether dexmedetomidine, a sedative, can safely calm agitation in 70 COPD patients with psychosis who were using non-invasive breathing masks. The goal was to see if it could prevent the need for a breathing tube. Researchers measured how many patients needed invasive ventilation and tracked agitation levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine
What this could lead to: If it works, this could offer a way to calm agitated COPD patients on breathing support, possibly reducing the need for a breathing tube.
What could go wrong: This is a small, completed study with only 70 participants. Results may not apply to all patients, and sedation carries risks like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease psychotic disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPONSE OF AGITATED PATIENTS TO DEXMEDETOMIDINE

Contacts and locations

Locations

Tanta

Tanta, Tanta, 0020, Egypt

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