New steroid shot may keep surgery patients from feeling sick

NCT ID NCT06997419

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a longer-acting form of the steroid dexamethasone can better prevent nausea and vomiting after open surgery. Researchers will give 500 adults either the standard dexamethasone or the new version (dexamethasone palmitate) right before surgery. The goal is to see if the new drug works better and lasts longer with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone palmitate
What this could lead to
If it works, this could offer a more effective way to prevent nausea and vomiting after surgery, reducing discomfort for patients.
What could go wrong
This is an early-stage trial with no phase specified, so results are uncertain. The improvement over standard dexamethasone may be small or not clinically meaningful.

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fang Luo

    RECRUITING

    Beijing, 100050, China

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