New steroid shot may keep brain surgery patients from getting sick

NCT ID NCT06988124

Recruiting now Symptom relief Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a long-acting steroid called dexamethasone palmitate can better prevent nausea and vomiting after brain surgery compared to the standard steroid. About 500 adults having elective brain surgery will receive either the new drug or standard dexamethasone before their operation. The main goal is to see if fewer people feel sick in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone palmitate
What this could lead to: If it works, this could offer a more effective, longer-lasting option to prevent nausea and vomiting after brain surgery.
What could go wrong: This is a single-center, Phase-not-specified trial. The drug may not prove superior to standard dexamethasone, and side effects from steroids remain possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE NAUSEA AND VOMITING

Contacts and locations

Locations

Fang Luo
RECRUITING

Beijing, 100050, China

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