Could a simple steroid dose before hip surgery prevent confusion in seniors?

NCT ID NCT07651150

Completed Disease control Sponsor: Jinnah Postgraduate Medical Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether a single 4 mg dose of the steroid dexamethasone, given intravenously before hip fracture surgery, can lower the risk and severity of postoperative delirium in adults aged 60 and older. Delirium is a sudden state of confusion that often occurs after major surgery in older patients and can lead to longer hospital stays and worse outcomes. The study compares dexamethasone to a placebo in a double-blind fashion, meaning neither patients nor doctors know who receives the active drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone
What this could lead to: If it works, this could point toward a simple, low-cost way to prevent postoperative delirium in older adults after hip surgery.
What could go wrong: This is a small, single-center trial, so results may not apply broadly. Delirium is complex and a single steroid dose may not be enough to prevent it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

delirium Emergence Delirium hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DELIRIUM - POSTOPERATIVE HIP FRACTURE SURGERIES STEROID

Contacts and locations

Locations

JPMC Karachi

Karachi, Sindh, Pakistan

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