Heart surgery showdown: could a simple gas beat standard anesthesia?

NCT ID NCT07116733

Recruiting now Disease control Sponsor: Xijing Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two anesthetics—desflurane gas and propofol—during coronary artery bypass surgery. Researchers want to see if desflurane helps prevent major heart problems like heart attack or heart failure within 30 days after surgery. About 3,560 adults having planned bypass surgery will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: desflurane (inhaled anesthetic)
What this could lead to: If desflurane works better than propofol, it could become the preferred anesthetic for heart bypass surgery to lower the risk of serious heart complications after the operation.
What could go wrong: This is a large phase 3 trial, but it's still possible that desflurane offers no advantage over propofol. The study focuses on short-term outcomes (30 days), so long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY CORONARY ARTERY BYPASS GRAFTING

Contacts and locations

Locations

Cangzhou People's Hospital
NOT_YET_RECRUITING

Cangzhou, Hebei, China
Changhai Hospital
RECRUITING

Shanghai, China
Daping Hospital, Army Medical University
NOT_YET_RECRUITING

Chongqing, China
Fuzhou University Affiliated Provincial Hospital
NOT_YET_RECRUITING

Fuzhou, Fujian, China
Hebei General Hospital
NOT_YET_RECRUITING

Shijiazhuang, Hebei, China
Jiangsu Province Hospital
NOT_YET_RECRUITING

Nanjin, Jiangsu, China
Ningbo No.2 Hospital
NOT_YET_RECRUITING

Ningbo, Zhejiang, China
Sichuan Provincial People's Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, China
The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITING

Zhengzhou, Henan, China
The First Hospital of Hebei Medical University
NOT_YET_RECRUITING

Shijiazhuang, Hebei, China
Tianjin Chest Hospital
RECRUITING

Tianjin, Tianjin Municipality, China
Wuhan Asia Heart Hospital
NOT_YET_RECRUITING

Wuhan, Hubei, China
Xijing Hospital
RECRUITING

Xi'an, Shaanxi, 710032, China
Zhongshan Hospital, Fudan University
NOT_YET_RECRUITING

Shanghai, China

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