Can a simple cream stop radiation burns? early trial halted

NCT ID NCT05269160

Terminated Symptom relief Sponsor: Baylor College of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a cream called dermaprazole (a form of esomeprazole) to see if it could prevent or reduce skin burns caused by radiation therapy in women who had mastectomy for breast cancer. Only 3 women were enrolled before the trial was stopped early. The goal was to check safety and whether the cream might help, but the small size and early termination mean no firm conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dermaprazole cream (esomeprazole cream)
What this could lead to: If it works, this could point toward a simple cream to prevent or reduce painful skin burns from radiation therapy in breast cancer patients.
What could go wrong: This was a very small, early-phase trial that was terminated early with only 3 participants, so results are limited and may not apply broadly. The cream's effectiveness and safety are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm radiodermatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER RADIATION DERMATITIS

Contacts and locations

Locations

Baylor St. Luke's Medical Center

Houston, Texas, 77054, United States
Harris Health System - Smith Clinic

Houston, Texas, 77054, United States

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