Can your bone doctor treat your depression?
NCT ID NCT05976347
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether orthopaedic surgeons can safely screen for depression in patients recovering from a broken bone and offer treatment with common antidepressants like Prozac or Cymbalta. About 100 adults who score at least 5 on a depression questionnaire will be offered medication or a referral to behavioral health. The goal is to see if this approach improves depressive symptoms and is practical in a trauma clinic.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluoxetine (Prozac) or Duloxetine (Cymbalta)
What this could lead to
If successful, this could show that orthopaedic surgeons can effectively treat depression after a serious injury, improving recovery and quality of life.
What could go wrong
This is a small pilot study (100 people) testing existing drugs, not a new breakthrough. Results may not apply to all patients, and antidepressants have side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Wake Forest University Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••