New asthma drug shows promise in Long-Term safety check

NCT ID NCT05243680

Completed Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at the long-term safety of a drug called depemokimab in 641 adults and teenagers with severe asthma caused by a type of white blood cell called eosinophils. Participants had already completed earlier studies and received the drug for another 12 months. The main goal was to track side effects and whether the body made antibodies against the drug. This is a disease-control treatment, not a cure, as asthma requires ongoing management.

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Conditions

The condition(s) this trial relates to.

asthma T2-high asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

Locations

GSK Investigational Site

Mobile, Alabama, 36608, United States
GSK Investigational Site

Lancaster, California, 93534, United States
GSK Investigational Site

Colorado Springs, Colorado, 80923, United States
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Lafayette, Colorado, 80026, United States
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Coral Gables, Florida, 33134, United States
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Hialeah, Florida, 33013, United States
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Loxahatchee Groves, Florida, 33470, United States
GSK Investigational Site

Miami, Florida, 33144, United States
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Miami, Florida, 33173, United States
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Miami, Florida, 33186, United States
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Orlando, Florida, 32806, United States
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Savannah, Georgia, 31406, United States
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Normal, Illinois, 61761, United States
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Lexington, Kentucky, 40509, United States
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Ypsilanti, Michigan, 48197, United States
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Northfield, New Jersey, 08225, United States
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Toms River, New Jersey, 08755, United States
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The Bronx, New York, 10461, United States
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Gastonia, North Carolina, 28054, United States
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Huntersville, North Carolina, 28078, United States
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Winston-Salem, North Carolina, 27103, United States
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DuBois, Pennsylvania, 15801, United States
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Allen, Texas, 75013, United States
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Boerne, Texas, 78006, United States
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Dallas, Texas, 75225, United States
GSK Investigational Site

Kerrville, Texas, 78028, United States
GSK Investigational Site

San Antonio, Texas, 78207, United States
GSK Investigational Site

San Antonio, Texas, 78229, United States
GSK Investigational Site

Bellingham, Washington, 98225, United States
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Coffs Harbour, New South Wales, 2450, Australia
GSK Investigational Site

South Brisbane, Queensland, 4101, Australia
GSK Investigational Site

Sherwood Park, Alberta, T8H 0N2, Canada
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Kamloops, British Columbia, V2C 5T1, Canada
GSK Investigational Site

Ajax, Ontario, L1S 2J5, Canada
GSK Investigational Site

Ottawa, Ontario, K1G 6C6, Canada
GSK Investigational Site

Changsha, Hunan, 410013, China
GSK Investigational Site

Changchun, 130021, China
GSK Investigational Site

Changchun, 132011, China
GSK Investigational Site

Chengdu, 610041, China
GSK Investigational Site

Guangzhou, 510080, China
GSK Investigational Site

Guangzhou, 510120, China
GSK Investigational Site

Guangzhou, 510150, China
GSK Investigational Site

Guangzhou, 510180, China
GSK Investigational Site

Haikou, 570311, China
GSK Investigational Site

Hangzhou, 310009, China
GSK Investigational Site

Hefei, 230001, China
GSK Investigational Site

Hohhot, 10017, China
GSK Investigational Site

Jinan, 250014, China
GSK Investigational Site

Shanghai, 200040, China
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Shanghai, 200090, China
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Shenyang, 110004, China
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Shenyang, 110016, China
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Ürümqi, 830054, China
GSK Investigational Site

Wenzhou, 323027, China
GSK Investigational Site

Wuhan, 430030, China
GSK Investigational Site

Xuzhou, 221006, China
GSK Investigational Site

Brno, 625 00, Czechia
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Hradec Králové, 500 05, Czechia
GSK Investigational Site

Jindřichův Hradec, 377 01, Czechia
GSK Investigational Site

Strakonice, 38601, Czechia
GSK Investigational Site

Tábor, 390 02, Czechia
GSK Investigational Site

Teplice, 415 01, Czechia
GSK Investigational Site

Caen, 14033, France
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Cholet, 49300, France
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Marseille, 13015, France
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Strasbourg, 67091, France
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Berlin, 10367, Germany
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Frankfurt, 60389, Germany
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Hamburg, 22299, Germany
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Koblenz, 56068, Germany
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Leipzig, 04275, Germany
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Magdeburg, 39120, Germany
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Neu-Isenburg, 63263, Germany
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Gödöllő, 2100, Hungary
GSK Investigational Site

Mosonmagyaróvár, 9200, Hungary
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Szigetvár, 7900, Hungary
GSK Investigational Site

Brescia, 25123, Italy
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Foggia, 71122, Italy
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Messina, 98158, Italy
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Milan, 20122, Italy
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Monserrato CA, 09042, Italy
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Palermo, 90127, Italy
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Pavia, 27100, Italy
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Roma, 168, Italy
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Rozzano MI, 20089, Italy
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Siena, 53100, Italy
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Varese, 21049, Italy
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Aichi, 470-1192, Japan
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Aichi, 489-8642, Japan
GSK Investigational Site

Chiba, 275-8580, Japan
GSK Investigational Site

Fukuoka, 802-0052, Japan
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Fukuoka, 811-1394, Japan
GSK Investigational Site

Fukuoka, 813-0017, Japan
GSK Investigational Site

Fukushima, 960-1295, Japan
GSK Investigational Site

Hiroshima, 734-8530, Japan
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Hokkaido, 053-8506, Japan
GSK Investigational Site

Hokkaido, 064-0804, Japan
GSK Investigational Site

Kagawa, 761-8073, Japan
GSK Investigational Site

Kagawa, 762-8550, Japan
GSK Investigational Site

Kagoshima, 890-8520, Japan
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Kanagawa, 231-8682, Japan
GSK Investigational Site

Kanagawa, 232-0024, Japan
GSK Investigational Site

Niigata, 951-8520, Japan
GSK Investigational Site

Okayama, 702-8055, Japan
GSK Investigational Site

Saga, 843-0393, Japan
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Tokyo, 103-0027, Japan
GSK Investigational Site

Tokyo, 141-8625, Japan
GSK Investigational Site

Tokyo, 158-0097, Japan
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Tokyo, 185-0014, Japan
GSK Investigational Site

Tokyo, 204-8585, Japan
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Gdansk, 80-214, Poland
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Kielce, 25-355, Poland
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Krakow, 30-033, Poland
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Krakow, 31-624, Poland
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Lodz, 90-242, Poland
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Lublin, 20-552, Poland
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Ostrowiec Świętokrzyski, 27-400, Poland
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Rzeszów, 35-051, Poland
GSK Investigational Site

Strzelce Opolskie, 47-120, Poland
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Barcelona, 08006, Spain
GSK Investigational Site

Benalmádena, 29631, Spain
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Girona, 17005, Spain
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Granada, 18014, Spain
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Madrid, 28031, Spain
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Madrid, CP 28041, Spain
GSK Investigational Site

Palma de Mallorca, 07010, Spain
GSK Investigational Site

Pozuelo de AlarcOn Madr, 28223, Spain
GSK Investigational Site

Santiago de Compostela, 15706, Spain
GSK Investigational Site

Valencia, 46015, Spain
GSK Investigational Site

Zaragoza, 50009, Spain
GSK Investigational Site

Kaohsiung City, 807, Taiwan
GSK Investigational Site

Taichung, 40705, Taiwan
GSK Investigational Site

Bradford, BD9 6RJ, United Kingdom
GSK Investigational Site

Chertsey, KT16 0PZ, United Kingdom
GSK Investigational Site

London, EC1M 6BQ, United Kingdom
GSK Investigational Site

Manchester, M8 5RB, United Kingdom
GSK Investigational Site

Nottingham, NG5 1PB, United Kingdom

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