Can a patient's own blood proteins help dental implants heal better?

NCT ID NCT07725029

Completed Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests two bone-grafting materials placed around dental implants immediately after tooth extraction in the front upper jaw. One group receives a graft made from processed tooth dentin, while the other gets dentin mixed with a concentrate of the patient's own blood proteins (platelet-rich fibrin). The goal is to see which approach leads to better implant stability during healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: demineralized dentin matrix with or without injectable platelet-rich fibrin
What this could lead to: If adding platelet-rich fibrin improves bone healing, it could lead to stronger, longer-lasting dental implants in the aesthetic zone.
What could go wrong: This is a small, early-stage trial with only 32 participants, so results may not apply broadly. Graft materials can sometimes fail to integrate or cause infection.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOOTH EXTRACTION

Contacts and locations

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Locations

Mansoura

Al Mansurah, Egypt

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