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Your extracted tooth may become the next bone graft

NCT ID NCT07789262

Disease control Sponsor: Ankara Yildirim Beyazıt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This trial tests whether a graft made from a patient's own extracted tooth can preserve the jawbone that normally shrinks after tooth removal. Researchers compare four approaches: no graft, dentin graft alone, dentin graft combined with platelet-rich fibrin (PRF) from the patient's blood, and a standard freeze-dried bone allograft. Four months later, they take small bone samples to measure new bone formation, blood vessel growth, and a bone-building protein. The goal is to see if the patient's own tooth, which would otherwise be thrown away, can work as well as or better than current bone substitutes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Autogenous dentin graft, alone or combined with platelet-rich fibrin (PRF), compared with freeze-dried bone allograft or no grafting
What this could lead to
If it works, this could turn a discarded tooth into a low-cost, effective way to preserve jawbone after extraction, potentially reducing the need for additional bone-building procedures before dental implants.
What could go wrong
This is a small, early-stage study with only 9 participants, so results may not apply broadly. The graft material is processed from the patient's own tooth, and outcomes depend on individual healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

9 people

The number who actually took part.

Started

Dec 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Systemically healthy individuals (ASA I-II) * Age 18 years or older * Presence of a tooth requiring extraction, radiographically confirmed to be non-infected Exclusion Criteria: * Presence of acute infection at the extraction site * Advanced systemic disease * Use of medications known to affect bone metabolism * Current smoking or alcohol use * Anticipated non-compliance with scheduled follow-up visits

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Tooth extraction

Contacts and locations

Locations

  • Ankara Yıldırım Beyazıt University, Faculty of Dentistry

    Ankara, Turkey (Türkiye)

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