Dengue vaccine shows promise in massive child trial
NCT ID NCT02747927
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new dengue vaccine in over 20,000 healthy children aged 4 to 16 years. The goal was to see if two doses could prevent dengue fever caused by any of the four dengue virus types. The vaccine was given as a shot under the skin and compared to a placebo. Results showed the vaccine reduced the number of dengue cases and hospitalizations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Associacao Obras Sociais Irma Dulce Hospital Santo Antonio
Salvador, Estado de Bahia, 40415-000, Brazil
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Calle Alexander Fleming No. 90 Esquina 37, Ensanche La Fe
Santo Domingo, Distrito Nacional Santo Domingo, 10514, Dominican Republic
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Centro De Vacunacion Internacional, S.A. (Cevaxin)
Panama City, 10662, Panama
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Centro De Vacunacion Internacional, S.A. (Cevaxin) Sede 24 de Diciembre
Panama City, Panama
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Centro De Vacunacion Internacional, S.A. (Cevaxin) Sede Plaza Carolina
Panama City, Panama
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Centro De Vacunacion Internacional, S.A.(Cevaxin) - La Chorrera
Panama City, Panama
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Centro de Atencion e Investigacion Medica S.A - CAIMED - Aguazul - PPDS-PV
Aguazul, Casanare Department, Colombia
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Centro de Atencion e Investigacion Medica S.A - CAIMED - Yopal - PPDS-PV
Yopal, Casanare Department, Colombia
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Centro de Atencion e Investigacion Medica S.A. - CAIMED - Acacias - PPDS-PV
Acacías, Meta Department, 507001, Colombia
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Centro de Estudios em Infectologia Pediatrica SAS (CEIP S.A.S)
Cali, San Fernando, Colombia
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Centro de Estudos e Pesquisa em Molestias Infecciosas LTDA (CPCLIN)
Cidade Alta, Natal - RN, 59025-050, Brazil
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Colombo North Teaching Hospital
Ragama, 11010, Sri Lanka
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Colombo South Teaching Hospital
Dehiwala, 10250, Sri Lanka
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Dela Salle Health Sciences Institute
Dasmariñas, Cavite, 4114, Philippines
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Hospital Maternidad Nuestra Senora de Altagracia
Santo Domingo, Distrito Nacional Santo Domingo, 10204, Dominican Republic
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Lady Ridgeway Hospital for Children
Colombo, 00800, Sri Lanka
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Las Pinas Health Center A
Las Piñas, Philippines
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Las Pinas Health Center D
Las Piñas, Philippines
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Negombo General Hospital
Negombo, 11500, Sri Lanka
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Philippines-AFRIMS Virology Research Unit
Cebu City, Cebu, 6000, Philippines
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Phramongkutklao Hospital
Bangkok, Bangkok, 10400, Thailand
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Research Institute for Tropical Medicine
City of Muntinlupa, 1781, Philippines
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Srinagarind Hospital
Khon Kaen, 40002, Thailand
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The Hospital for Tropical Diseases
Bangkok, Bangkok, 10270, Thailand
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Universidad Nacional Autonoma de Nicaragua
León, Nicaragua
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Universidade Federal Do Espirito Santo Hospital Universitario Cassiano Antonio de Moraes HUCAM
Vitória, Espírito Santo, 29040-091, Brazil
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Universidade Federal de Mato Grosso do Sul
Campo Grande, Mato Grosso do Sul, 79070-900, Brazil
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University of the Philippine Manila
Ermita, 1000, Philippines
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