Major trial tests new dengue shot for kids

NCT ID NCT02747927

First seen Nov 19, 2025 · Last updated Apr 22, 2026 · Updated 12 times

Summary

This study tested whether a new two-dose dengue vaccine could prevent dengue fever in healthy children aged 4 to 16. Over 20,000 children participated, with some receiving the vaccine and others receiving a placebo. Researchers measured how well the vaccine prevented symptomatic dengue and related hospitalizations.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Associacao Obras Sociais Irma Dulce Hospital Santo Antonio

    Salvador, Estado de Bahia, 40415-000, Brazil

  • Calle Alexander Fleming No. 90 Esquina 37, Ensanche La Fe

    Santo Domingo, Distrito Nacional Santo Domingo, 10514, Dominican Republic

  • Centro De Vacunacion Internacional, S.A. (Cevaxin)

    Panama City, 10662, Panama

  • Centro De Vacunacion Internacional, S.A. (Cevaxin) Sede 24 de Diciembre

    Panama City, Panama

  • Centro De Vacunacion Internacional, S.A. (Cevaxin) Sede Plaza Carolina

    Panama City, Panama

  • Centro De Vacunacion Internacional, S.A.(Cevaxin) - La Chorrera

    Panama City, Panama

  • Centro de Atencion e Investigacion Medica S.A - CAIMED - Aguazul - PPDS-PV

    Aguazul, Casanare Department, Colombia

  • Centro de Atencion e Investigacion Medica S.A - CAIMED - Yopal - PPDS-PV

    Yopal, Casanare Department, Colombia

  • Centro de Atencion e Investigacion Medica S.A. - CAIMED - Acacias - PPDS-PV

    Acacías, Meta Department, 507001, Colombia

  • Centro de Estudios em Infectologia Pediatrica SAS (CEIP S.A.S)

    Cali, San Fernando, Colombia

  • Centro de Estudos e Pesquisa em Molestias Infecciosas LTDA (CPCLIN)

    Cidade Alta, Natal - RN, 59025-050, Brazil

  • Colombo North Teaching Hospital

    Ragama, 11010, Sri Lanka

  • Colombo South Teaching Hospital

    Dehiwala, 10250, Sri Lanka

  • Dela Salle Health Sciences Institute

    Dasmariñas, Cavite, 4114, Philippines

  • Hospital Maternidad Nuestra Senora de Altagracia

    Santo Domingo, Distrito Nacional Santo Domingo, 10204, Dominican Republic

  • Lady Ridgeway Hospital for Children

    Colombo, 00800, Sri Lanka

  • Las Pinas Health Center A

    Las Piñas, Philippines

  • Las Pinas Health Center D

    Las Piñas, Philippines

  • Negombo General Hospital

    Negombo, 11500, Sri Lanka

  • Philippines-AFRIMS Virology Research Unit

    Cebu City, Cebu, 6000, Philippines

  • Phramongkutklao Hospital

    Bangkok, Bangkok, 10400, Thailand

  • Research Institute for Tropical Medicine

    City of Muntinlupa, 1781, Philippines

  • Srinagarind Hospital

    Khon Kaen, 40002, Thailand

  • The Hospital for Tropical Diseases

    Bangkok, Bangkok, 10270, Thailand

  • Universidad Nacional Autonoma de Nicaragua

    León, Nicaragua

  • Universidade Federal Do Espirito Santo Hospital Universitario Cassiano Antonio de Moraes HUCAM

    Vitória, Espírito Santo, 29040-091, Brazil

  • Universidade Federal de Mato Grosso do Sul

    Campo Grande, Mato Grosso do Sul, 79070-900, Brazil

  • University of the Philippine Manila

    Ermita, 1000, Philippines

Conditions

Explore the condition pages connected to this study.