New dengue vaccine trial shows promise for india

NCT ID NCT06060067

Completed ⭐️ VACCINE ⭐️ Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tested Takeda's dengue vaccine (TDV) in 480 healthy people aged 4 to 60 in India. Participants received two doses of either the vaccine or a placebo, three months apart. The main goals were to check for side effects and measure the body's immune response against all four types of dengue virus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Takeda's dengue vaccine (TDV, also called TAK-003)
What this could lead to: If successful, this vaccine could help protect people in India from dengue fever, a serious mosquito-borne disease.
What could go wrong: This is a Phase 3 trial focused on safety and immune response, not yet proven to prevent dengue in the real world. Side effects like injection site pain or fever are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dengue disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEERS

Contacts and locations

Locations

BGS Global Institute of Medical Sciences (BGS-GIMS) #67, BGS Health & Education City, Uttarahalli Main Road, Kengeri

Bangalore, Karnataka, 560060, India
Chettinad Academy of Research and Education, Chettinad Health City, SH,49A, Dist. Kelambakkam

Pudupākkam, Tamil Nadu, 603 103, India
IPGME&R and SSKM Hospital, 244 AJC Bose Road

Kolkata, 700020, India
KEM Hospital Research Centre, Sandar Moodliar Road, Rasta Peth

Pune, 411011, India
King George Hospital

Visakhapatnam, 530002, India
King George's Medical University, Department of Medicine, Chowk

Lucknow, 226003, India
Maulana Azad Medical College & Associated Lok Nayak, Govind Ballabh Pant Hospitals and Guru Nanak Eye Center

New Delhi, 110002, India
Preventive and Therapeutic Clinical Trial Unit (PTCTU), Dept. of Community Medicine, Institute of Medical Science and SUM Hospital, K-8, Kalinga Nagar

Bhubaneswar, 751003, India
SRM Medical College Hospital & Research Centre, SRM Nagar, Potheri

Kattankulathur, 603203, India
Suyog Hospital, 2nd Floor, B-Wing, Krushi Utpanna Bazar, Samiti Sankul, Dindori Rd, Panchavati

Nashik, 422003, India

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