Dengue vaccine under the microscope: will it keep kids out of the hospital?

NCT ID NCT06843226

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the dengue vaccine (TDV) helps prevent hospital stays due to dengue in children and teens in Thailand, Indonesia, and Malaysia. Researchers will follow 70,000 participants for 3 years, comparing those who got the vaccine with those who did not. The goal is to gather real-world data on how well the vaccine works, especially against less common dengue types.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could confirm that the dengue vaccine effectively prevents severe dengue leading to hospitalization in children and teens.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It is also limited to specific countries and may not apply everywhere.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Fakultas Kedokteran Lambung Mangkurat

    RECRUITING

    Banjarmasin, South Kalimantan, 70122, Indonesia

  • Fakultas Kedokteran Universitas Indonesia

    RECRUITING

    Jakarta Pusat, 10430, Indonesia

  • Fakultas Kedokteran Universitas Sriwijaya

    RECRUITING

    Palembang, South Sumatra, 30662, Indonesia

  • Nakhon Phanom Hospital

    ACTIVE_NOT_RECRUITING

    Nakhon Phanom, 48000, Thailand

  • Pattaya Patamakhun Hospital

    ACTIVE_NOT_RECRUITING

    Chon Buri, 20150, Thailand

  • Phra Nakhon Si Ayutthaya Hospital

    ACTIVE_NOT_RECRUITING

    Phra Nakhon Si Ayutthaya, 13000, Thailand

  • Universiti Malaya Medical Centre

    NOT_YET_RECRUITING

    Kuala Lumpur, 59100, Malaysia

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