Could a One-Time injection of your own immune cells protect your kidneys?

NCT ID NCT06866158

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial is testing whether a single injection of a person's own immune cells (dendritic cells and lymphocytes) can reduce kidney damage in type 2 diabetes. The cells are processed in a lab and then given back under the skin. Researchers will measure urine protein levels and kidney function over four weeks in 80 adults. The goal is to see if this approach can calm inflammation and protect the kidneys.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
autologous dendritic cells and lymphocytes matured with SARS-CoV-2 S protein
What this could lead to
If it works, this could point toward a new way to slow or reverse kidney damage in people with type 2 diabetes, potentially reducing the need for dialysis or transplant.
What could go wrong
This is a very early (Phase 1/2), small, single-arm trial with no placebo group, so results may be due to chance or natural variation. The treatment uses a coronavirus protein to mature the cells, which is unusual and its safety and effectiveness are unproven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gatot Soebroto Central Army Hospital

    Jakarta Pusat, DKI Jakarta - Jakarta, 10410, Indonesia

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