Neck surgery may help clear Alzheimer's toxins from the brain
NCT ID NCT07669272
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a one-time microsurgery that connects lymphatic vessels in the neck to veins, aiming to improve drainage of waste proteins from the brain. Fifty-nine people with severe Alzheimer's will receive the surgery plus standard medication. Researchers will measure changes in cognitive function and brain scans over 12 months to see if the procedure is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Deep Cervical Lymphovenous Anastomosis (a microsurgical procedure to connect lymphatic vessels to neck veins)
What this could lead to
If successful, this could offer a new way to slow cognitive decline in severe Alzheimer's by helping the brain clear toxic proteins.
What could go wrong
This is a very early, small study with no control group, so results may not be reliable. Surgery carries risks like infection or anesthesia complications, and the benefit is unproven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital of Army Medical University (Southwest Hospital)
Chongqing, Chongqing Municipality, 400038, China
Contact Phone: •••-•••-•••• Email: •••••@•••••