New cancer drug trial tests immune system 'Decoy' to fight advanced tumors

NCT ID NCT05651022

Summary

This early-stage study is testing a new immunotherapy drug called DECOY20, both alone and combined with another cancer drug (tislelizumab), in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe doses, check for side effects, and see early signs of whether the treatment helps shrink tumors. About 120 adults with specific advanced cancers like lung, liver, colorectal, and pancreatic cancer will participate.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Atlantic Health System

    Morristown, New Jersey, 07960, United States

  • Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio, 44195, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Gabrail Cancer & Research Center

    Canton, Ohio, 44718, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, 92663, United States

  • Prisma Health Cancer Institute-ITOR

    Greenville, South Carolina, 29605, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

  • The Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • UH Seidman Cancer Center

    Cleveland, Ohio, 44106, United States

  • University of Southern California- Norris Cancer Center

    Los Angeles, California, 90033, United States

  • Washington University, Siteman Cancer Center

    St Louis, Missouri, 63108, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.