Exercise may shield blood vessels from chemotherapy damage, study suggests
NCT ID NCT05223322
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study looks at whether a 16-20 week exercise and coaching program can reduce inflammation and protect blood vessel health in Black and White women undergoing chemotherapy for breast cancer. Researchers will measure fitness, blood vessel function, and quality of life. The goal is to understand how exercise might help prevent long-term heart problems caused by cancer treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a 16-20 week exercise and coaching program called Taking Charge during Treatment (TCT)
- What this could lead to
- If successful, this could show that a structured exercise program helps protect blood vessels from chemotherapy damage, potentially reducing long-term heart risks in breast cancer survivors.
- What could go wrong
- This is an early-stage observational study with only 80 participants, so results may not apply to all groups. The exercise program may be difficult for some to complete, and the study does not test a drug or cure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medical College of Wisconsin
Wauwatosa, Wisconsin, 53226, United States
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University of Illinois Chicago
Chicago, Illinois, 60607, United States
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