Could a chemo drug help patients with rare bone marrow cancer?
NCT ID NCT00095784
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests the drug decitabine in 21 patients with advanced myelofibrosis, a bone marrow cancer that causes scarring and anemia. The goal is to see if decitabine can improve blood counts and reduce the need for transfusions. Researchers are also monitoring side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Decitabine (a chemotherapy drug)
What this could lead to
If it works, this could offer a treatment option for patients with advanced myelofibrosis who have no standard therapy.
What could go wrong
This is a small, early-phase trial with only 21 participants. The drug may cause side effects and may not improve outcomes for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Central Illinois Hematology Oncology Center
Springfield, Illinois, 62702, United States
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Decatur Memorial Hospital
Decatur, Illinois, 62526, United States
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Fort Wayne Medical Oncology and Hematology Inc-Parkview
Fort Wayne, Indiana, 46845, United States
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Illinois CancerCare-Peoria
Peoria, Illinois, 61615, United States
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Ingalls Memorial Hospital
Harvey, Illinois, 60426, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, 60201, United States
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Northern Indiana Cancer Research Consortium
South Bend, Indiana, 46628, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Oncology Care Associates PLLC
Saint Joseph, Michigan, 49085, United States
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Southern Illinois University School of Medicine
Springfield, Illinois, 62702, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States