New combo aims to boost immune attack on rare melanoma

NCT ID NCT05089370

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This early-phase trial tests whether adding an oral drug (DEC-C) to the immunotherapy nivolumab can help the immune system better fight advanced mucosal melanoma, a rare and hard-to-treat skin cancer. The study includes 8 adults with unresectable or metastatic disease. The main goals are to check safety and find the best dose, while also measuring tumor shrinkage.

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Contacts and locations

Locations

  • University of Colorado Hospital

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.