New test may help DCIS patients avoid unnecessary radiation
NCT ID NCT03448926
First seen Apr 24, 2026 · Last updated Jun 22, 2026 · Updated 10 times
Summary
This study looks at how a test called DCISionRT affects treatment decisions for people with ductal carcinoma in situ (DCIS), a very early form of breast cancer. The test predicts the risk of the cancer coming back and whether radiation therapy would help. Researchers will track whether doctors change their treatment recommendations after seeing the test results. The goal is to see if the test helps tailor treatments, possibly sparing some patients from unnecessary radiation.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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AHN Allegheny General Hospital
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Arizona Center for Cancer Care
RECRUITINGScottsdale, Arizona, 85258, United States
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Baptist MD Anderson Cancer Center
RECRUITINGJacksonville, Florida, 32207, United States
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BayCare Health System
RECRUITINGTampa, Florida, 33607, United States
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Cleveland Clinic Akron General
RECRUITINGAkron, Ohio, 44302, United States
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Cleveland Clinic Foundation-Taussig Cancer Inst
RECRUITINGCleveland, Ohio, 44195, United States
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Compass Oncology
RECRUITINGTigard, Oregon, 97223, United States
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Comprehensive Breast Care
RECRUITINGTroy, Michigan, 48098, United States
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Corewell Health William Beaumont University Center
RECRUITINGRoyal Oak, Michigan, 48073, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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Emory University Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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Endeavor Health (Northshore)
RECRUITINGEvanston, Illinois, 60201, United States
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Maimonides Cancer Center
RECRUITINGBrooklyn, New York, 11220, United States
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MedStar Health Research Institute
RECRUITINGBaltimore, Maryland, 21237, United States
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NYU - Long Island
RECRUITINGMineola, New York, 11501, United States
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NYU - Manhattan
RECRUITINGNew York, New York, 10016, United States
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Nashville Breast Center
RECRUITINGNashville, Tennessee, 37203, United States
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Northwell Health Center for Advanced Medicine
RECRUITINGLake Success, New York, 11042, United States
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Sidney Kimmel Comprehensive Cancer Ctr - Jefferson
RECRUITINGPhiladelphia, Pennsylvania, 19027, United States
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St Luke's University Health Network
RECRUITINGEaston, Pennsylvania, 18045, United States
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Sutter Health
RECRUITINGSan Mateo, California, 94401, United States
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Texas Oncology
RECRUITINGPlano, Texas, 75093, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43212, United States
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75235, United States
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University of California San Diego
RECRUITINGLa Jolla, California, 92093, United States
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University of Colorado Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
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University of South Florida
RECRUITINGTampa, Florida, 33613, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could show that the DCISionRT test helps doctors and patients make more informed treatment decisions, potentially reducing unnecessary treatments.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test if the test improves health outcomes. Results may vary across different patient groups.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.