New cocktail targets Hard-to-Treat myeloma

NCT ID NCT04176718

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a combination of four drugs (daratumumab, carfilzomib, pomalidomide, and dexamethasone) in people whose multiple myeloma has returned or stopped responding to prior treatments. The goal is to see how many patients achieve tumor shrinkage and how long the benefit lasts. About 43 adults aged 18โ€“80 with relapsed or refractory multiple myeloma will take part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02155, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

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