Could a diabetes pill boost chemo response in breast cancer? new study investigates.

NCT ID NCT05989347

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study looks at whether adding dapagliflozin, a diabetes drug, to standard chemotherapy changes insulin-related markers in the blood. It involves 20 women with early-stage HER2-negative breast cancer who also have high insulin levels. The goal is to gather safety data and understand how the drug affects insulin resistance, not to treat the cancer directly.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yale Cancer Center Smilow Cancer Hospital

    RECRUITING

    New Haven, Connecticut, 06520, United States

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