Could a diabetes pill boost breast cancer treatment? new study explores link between insulin and chemo

NCT ID NCT05989347

First seen May 27, 2026 · Last updated Jun 16, 2026 · Updated 4 times

Summary

This early-phase study is testing whether adding dapagliflozin, a diabetes drug, to standard chemotherapy can improve insulin resistance in women with early-stage HER2-negative breast cancer who have high insulin levels. About 20 participants will receive the drug alongside chemo to see how it affects metabolic markers. The goal is to gather safety and biomarker data, not to cure the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale Cancer Center Smilow Cancer Hospital

    RECRUITING

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.