Could a methadone derivative ease restless legs?
NCT ID NCT04145674
First seen Mar 18, 2026 · Last updated May 15, 2026 · Updated 5 times
Summary
This study tests a drug called d-methadone in 50 people with moderate to very severe restless legs syndrome (RLS). Participants take the drug or a placebo daily for 30 days. The goal is to see if it reduces RLS symptoms and improves sleep quality.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Neurologie / Schlaflabor Kantonsspital Graubünden
Chur, 7000, Switzerland
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Schlaf-Wach-Epilepsie Zentrum, Inselspital
Bern, Switzerland
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Sleep Center, IRCCS San Raffaele
Milan, Italy
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Sleep Center, Neurocenter of Southern Switzerland
Lugano, 6900, Switzerland
Conditions
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