Simple urine test may spot kidney trouble early in kids with cancer

NCT ID NCT02822404

First seen Apr 02, 2026 · Last updated Jun 22, 2026 · Updated 14 times

Summary

This study looked at whether a substance called cystatin C, measured in urine and blood, can detect kidney damage from chemotherapy drugs cisplatin and ifosfamide in children. Researchers followed 42 children and compared cystatin C levels to standard kidney tests. The goal was to find a simpler, less burdensome way to monitor kidney health during cancer treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Toulouse

    Toulouse, 31059, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If cystatin C proves reliable, it could offer a simpler, less invasive way to monitor kidney health in children undergoing chemotherapy.

What could go wrong

This is a small, completed observational study. The marker may not be accurate enough to replace current tests, and results may not apply to all children or treatments.

Conditions

The condition(s) this trial relates to.

kidney disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.