New combo treatment for Sjögren's dry eye shows promise in small trial

NCT ID NCT07171710

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares using cyclosporine eye drops alone versus combining them with absorbable punctal plugs for dry eye caused by Sjögren's syndrome. Thirty participants will receive the drops in both eyes and a plug in one eye to see if the combination improves symptoms better. The goal is to find a more effective way to manage this chronic condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

0.05% cyclosporine A eye drops and absorbable punctal plugs

What this could lead to

If successful, this combination could offer better relief for dry eye symptoms in Sjögren's syndrome patients than drops alone.

What could go wrong

This is a small, early-stage study with only 30 participants, so results may not apply widely. The punctal plugs are temporary and may cause irritation or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome Sjogren syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tianjin Eye Hospital

    Tianjin, Tianjin Municipality, China