New combo treatment for Sjögren's dry eye shows promise in small trial
NCT ID NCT07171710
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study compares using cyclosporine eye drops alone versus combining them with absorbable punctal plugs for dry eye caused by Sjögren's syndrome. Thirty participants will receive the drops in both eyes and a plug in one eye to see if the combination improves symptoms better. The goal is to find a more effective way to manage this chronic condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 0.05% cyclosporine A eye drops and absorbable punctal plugs
- What this could lead to
- If successful, this combination could offer better relief for dry eye symptoms in Sjögren's syndrome patients than drops alone.
- What could go wrong
- This is a small, early-stage study with only 30 participants, so results may not apply widely. The punctal plugs are temporary and may cause irritation or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tianjin Eye Hospital
Tianjin, Tianjin Municipality, China
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