New drug cocktail aims to save kidneys from rare protein disease

NCT ID NCT06083922

Recruiting now Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests a combination of four drugs (CyBorD plus daratumumab) in 20 people with a rare kidney condition caused by abnormal proteins. The goal is to see if the treatment is safe and can improve kidney function. Participants must have a confirmed diagnosis of multiple myeloma or related kidney disease.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MONOCLONAL GAMMOPATHY OF RENAL SIGNIFICANCE MULTIPLE MYELOMA

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center Suffolk - Commack (Limited Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States
Mount Sinai Hospital (Data Collection Only)
COMPLETED

New York, New York, 10029, United States
Tufts Medical Center (Data Collection Only)
ACTIVE_NOT_RECRUITING

Boston, Massachusetts, 02111, United States
University of North Carolina (Data Collection Only)
RECRUITING

Chapel Hill, North Carolina, 27514, United States
Weill Cornell Medical Center (Data Collection Only)
NOT_YET_RECRUITING

New York, New York, 10021, United States

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