New drug tested in fight against recurrent childhood brain cancer

NCT ID NCT03904862

Summary

This study tested an oral drug called CX-4945 in children and young adults whose medulloblastoma, a type of brain tumor, had come back after standard treatment. The main goals were to find the safest and most effective dose for younger children and to see if the drug could shrink tumors in older patients. The trial also included a surgical part to measure how much of the drug reached the tumor tissue.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90026, United States

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania, 15201, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • St. Jude Children Research Hospital

    Memphis, Tennessee, 38105, United States

  • Stanford University and Lucile Packard Children's Hospital

    Palo Alto, California, 94304, United States

  • University of Florida

    Gainesville, Florida, 32608, United States

Conditions

Explore the condition pages connected to this study.