New drug tested in fight against recurrent childhood brain cancer
NCT ID NCT03904862
Summary
This study tested an oral drug called CX-4945 in children and young adults whose medulloblastoma, a type of brain tumor, had come back after standard treatment. The main goals were to find the safest and most effective dose for younger children and to see if the drug could shrink tumors in older patients. The trial also included a surgical part to measure how much of the drug reached the tumor tissue.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90026, United States
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Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15201, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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St. Jude Children Research Hospital
Memphis, Tennessee, 38105, United States
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Stanford University and Lucile Packard Children's Hospital
Palo Alto, California, 94304, United States
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University of Florida
Gainesville, Florida, 32608, United States
Conditions
Explore the condition pages connected to this study.