Promising brain tumor drug trial halted early – what we know
NCT ID NCT03904862
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 31 times
Summary
This study tested a drug called CX-4945 in children whose SHH medulloblastoma (a brain tumor) had come back. The goal was to find the best dose and see if it could shrink tumors. The trial was stopped early, but it involved 21 participants and looked at how the drug worked in the body.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90026, United States
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Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15201, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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St. Jude Children Research Hospital
Memphis, Tennessee, 38105, United States
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Stanford University and Lucile Packard Children's Hospital
Palo Alto, California, 94304, United States
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University of Florida
Gainesville, Florida, 32608, United States
Conditions
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