New hope for patients whose cancers resist immunotherapy
NCT ID NCT03881488
First seen Apr 20, 2026 · Last updated May 13, 2026 · Updated 5 times
Summary
This early-stage study tested an experimental drug called CTX-471, given alone or with another immunotherapy (pembrolizumab), in 100 adults with advanced solid tumors that had stopped responding to standard PD-1/PD-L1 inhibitors. The main goal was to check safety and find the right dose. This is not a cure, but aims to control the disease in people with limited options.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NON SMALL CELL LUNG CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
-
Duke University School of Medicine
Durham, North Carolina, 27705, United States
-
Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
-
Hematology Oncology Associates Of The Treasure Coast
Port Saint Lucie, Florida, 34952, United States
-
Institute for Translational Oncology Research (ITOR)
Greenville, South Carolina, 29605, United States
-
Mary Crowley Cancer Research
Dallas, Texas, 75251, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Mt Sinai
New York, New York, 10029, United States
-
Ocala Oncology Center
Ocala, Florida, 34474, United States
-
Washington University School of Medicine, Siteman Cancer Center
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.