Blood test could spot lung cancer hidden in lung nodules
NCT ID NCT07615556
First seen May 31, 2026 · Last updated Jun 23, 2026 · Updated 6 times
Summary
This study is testing whether a blood test that looks for genetic changes (ctDNA mutations and methylation) can help detect lung cancer early in people who have suspicious lung nodules found on CT scans. Researchers will collect blood samples from 200 participants in Hong Kong and Vietnam at the start and after 6 months, and compare the results with follow-up CT scans. The goal is to see if the blood test can improve the accuracy of lung cancer diagnosis and reduce unnecessary procedures.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Hong Kong Queen Mary Hospital
Hong Kong, Hong Kong
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ctDNA mutations and methylation with SPOTMAS Lung assays (blood test)
What this could lead to
If successful, this blood test could help doctors identify lung cancer earlier in people with suspicious lung nodules, potentially reducing unnecessary procedures and improving outcomes.
What could go wrong
This is an early-stage observational study with only 200 participants. The test may not be accurate enough to replace current methods, and results may not apply to all populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.