Blood test may spot lung cancer sooner in High-Risk patients

NCT ID NCT07615556

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether a blood test that looks for genetic changes (ctDNA) can help detect lung cancer early in people who have suspicious lung nodules found on CT scans. Researchers will collect blood samples from 200 participants in Hong Kong and Vietnam at the start and after 6 months, and compare the results with follow-up CT scans. The goal is to see if the blood test can improve the accuracy of lung cancer diagnosis and reduce unnecessary procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ctDNA mutations and methylation with SPOTMAS Lung assays (blood test)
What this could lead to
If successful, this blood test could help doctors identify lung cancer earlier in people with suspicious lung nodules, potentially reducing unnecessary biopsies and improving outcomes.
What could go wrong
This is an early-stage study with only 200 participants, so results may not apply to everyone. The test might not be accurate enough to replace current methods, and false positives or negatives are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EARLY DETECTION OF LUNG CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Hong Kong Queen Mary Hospital

    Hong Kong, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.