Blood test may outshine scans for spotting hidden cancer after radiation

NCT ID NCT05710679

Recruiting now Knowledge-focused Sponsor: Centre Jean Perrin Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a simple blood test that looks for tumor DNA can better detect any cancer left behind after radiation therapy for advanced head and neck cancer. Current scans often give false alarms, leading to unnecessary procedures. The study will enroll 63 adults with newly diagnosed, advanced head and neck cancer who are scheduled for radiation. Researchers will compare blood test results with PET/CT scans to see which method more accurately identifies residual disease.

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Conditions

The condition(s) this trial relates to.

head and neck carcinoma head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED HEAD AND NECK CARCINOMA

Contacts and locations

Locations

CHU de Saint-Étienne
RECRUITING

Saint-Etienne, France
Centre Hospitalier Henri Mondor
NOT_YET_RECRUITING

Aurillac, 15000, France
Centre Jean PERRIN
RECRUITING

Clermont-Ferrand, Puy-de-Dôme, 63011, France
Hôpital de la Croix-Rousse
RECRUITING

Lyon, France

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