Can AI-Guided radiation tame lung tumors without the burn?

NCT ID NCT05785845

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial is testing a new radiation technique called CT-STAR for people with early-stage non-small cell lung cancer located near the center of the chest, where treatment is tricky. The approach uses a machine that takes CT images during each session and adapts the radiation plan in real time to spare nearby healthy organs. The goal is to see if this can safely deliver a shorter, more powerful course of radiation while reducing severe side effects compared to standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Computed tomography-guided stereotactic adaptive radiotherapy (CT-STAR) using the ETHOS system
What this could lead to
If successful, this approach could allow a shorter, more intense radiation course for hard-to-treat lung tumors while reducing severe side effects.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not apply broadly. There is still a risk of serious side effects from radiation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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