New hope for rare liver disease: phase 3 trial of CS0159 launches
NCT ID NCT07282353
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study tests a new drug called CS0159 in 135 adults with primary biliary cholangitis (PBC), a chronic liver disease. Participants must have had an inadequate response or intolerance to the standard treatment UDCA. The trial compares CS0159 to a placebo over 52 weeks to see if it improves liver function markers like ALP and bilirubin. The goal is to better control the disease, not cure it.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Guangdong Medical University
RECRUITINGZhanjiang, Guangdong, China
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Baoji People's Hospital
RECRUITINGBaoji, Shaanxi, China
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Beijing Friendship Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100050, China
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Beijing Youan Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100069, China
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China-Japan Friendship Hospital
RECRUITINGBeijing, Beijing Municipality, China
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Chongqing University Three Gorges Hospital
RECRUITINGChongqing, Chongqing Municipality, China
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Hangzhou Xixi Hospital
RECRUITINGHangzhou, Zhejiang, China
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Henan Provincial People's Hospital
RECRUITINGZhengzhou, Henan, China
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Jiangsu Province Hospital
RECRUITINGNanjing, Jiangsu, China
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Linyi People's Hospital
RECRUITINGLinyi, Shandong, China
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Mengchao Hepatobiliary Hospital Of Fujian Medical University
RECRUITINGFuzhou, Fujian, China
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Ningbo Medical Center Li Huili hospital
NOT_YET_RECRUITINGNingbo, Zhejiang, China
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Peking University Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, China
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Renji Hospital, School of Medicine, Shanghai Jiao Tong University
RECRUITINGShanghai, Shanghai Municipality, 200001, China
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Shanghai Jiao Tong University School of Medicine Ruijin Hospital
RECRUITINGShanghai, Shanghai Municipality, China
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Shenzhen Third People's Hospital
RECRUITINGShenzhen, Guangdong, China
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Taihe Hospital of Shiyan
RECRUITINGShiyan, Hubei, China
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Taizhou Hospital of Zhejiang Province
RECRUITINGTaizhou, Zhejiang, China
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The Affiliated Hospital of Qingdao University
RECRUITINGQingdao, Shandong, China
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The Fifth People's Hospital Of Wuxi
RECRUITINGWuxi, Jiangsu, China
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The Fifth People's Hospital of Suzhou
RECRUITINGSuzhou, Jiangsu, China
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The First Affiliated Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, China
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The First Affiliated Hospital of Guangxi Medical University
RECRUITINGNanning, Guangxi, China
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The First Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, China
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The First Affiliated Hospital of USTC Anhui Provincial Hospital
RECRUITINGHefei, Anhui, 230001, China
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The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITINGXi'an, Shaanxi, China
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The First Bethune Hospital of Jilin University
RECRUITINGChangchun, Jilin, China
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The First Hospital of China Medical University
RECRUITINGShenyang, Liaoning, China
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The Fourth Hospital Of Harbin Medical University
RECRUITINGHarbin, Heilongjiang, China
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The Fourth People's Hospital of Qinghai Province
NOT_YET_RECRUITINGXining, Qinghai, China
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The Second Affiliated Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, China
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The Second Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, China
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The Second Hospital of Nanjing
RECRUITINGNanjing, Jiangsu, China
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The Third People's Hospital of Zhenjiang
RECRUITINGZhenjiang, Jiangsu, China
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Tianjin First Central Hospital
RECRUITINGTianjin, Tianjin Municipality, China
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Tianjin Medical University General Hospital
RECRUITINGTianjin, Tianjin Municipality, China
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Tianjin Third Central Hospital
RECRUITINGTianjin, Tianjin Municipality, China
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West China Hospital, Sichuan University
RECRUITINGChengdu, Sichuan, China
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Xiamen Hospital of T.C,M.
RECRUITINGXiamen, Fujian, China
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Xiangya Hospital Central South University
RECRUITINGChangsha, Hunan, China
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Xin Hua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, China
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Zhongnan Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, Hubei, China
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Other studies related to the condition(s) this trial covers.
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