Freezing nerves could offer new hope for diabetic foot pain

NCT ID NCT06646731

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a procedure called cryoneurolysis, which uses a small probe to freeze nerves in the foot and block pain signals. It is for adults with painful diabetic neuropathy who have at least moderate pain daily. Thirty participants will be randomly assigned to receive either the real freezing treatment or a sham (fake) procedure, and researchers will compare pain levels one month later.

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Conditions

The condition(s) this trial relates to.

Chronic Pain diabetic neuropathy diabetic polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Diego

    La Jolla, California, 92129, United States