Freezing cancer cells: could cryoablation boost immunotherapy?

NCT ID NCT04150939

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding cryoablation—a procedure that freezes and kills cancer cells—can improve the effectiveness of standard immunotherapy in people with metastatic cancer. Fifteen participants will receive both treatments, and researchers will measure how many patients see their tumors shrink or disappear. The goal is to see if this combination can better control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cryoablation (freezing tumors) plus standard immunotherapy

What this could lead to

If it works, this could point toward a way to boost the effectiveness of immunotherapy for people with metastatic cancer.

What could go wrong

This is a very small early-phase trial with only 15 participants, so results may not apply broadly. The added procedure carries risks like infection or damage to nearby tissue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States